Correlation between the anatomical and functional human subthalamic nucleus.
Identifieur interne : 002580 ( Main/Exploration ); précédent : 002579; suivant : 002581Correlation between the anatomical and functional human subthalamic nucleus.
Auteurs : Wieslaw Nowinski [Singapour] ; A. Thirunavuukarasuu [Singapour] ; Jimin Liu [Singapour] ; Alim-Louis Benabid [France]Source :
- Stereotactic and Functional Neurosurgery [ 1011-6125 ] ; 2007.
Abstract
This work addresses the spatial correlation between the anatomical and functional human subthalamic nucleus (STN). The anatomical STN (A-STN), derived from the Schaltenbrand-Wahren brain atlas, is histology based. The functional STN (F-STN) is probabilistic, constructed from neuroelectrophysiological and neuroimaging data of 184 Parkinson's disease patients. The A-STN and F-STN are placed in the same space and compared in terms of mutual relative overlapping of anatomy with function. The F-STN and A-STN correlate well for medium and high probabilities of the F-STN. For probability p >or= 0.3, >95% of F-STN is inside the A-STN, and for p >or= 0.5, the complete F-STN is inside the A-STN for each left and right STN. Therefore, the F-STN for p = 0.5 can potentially be used for identification of the STN in neuroimages.
Url:
DOI: 10.1159/000097924
Affiliations:
- France, Singapour
- Auvergne-Rhône-Alpes, Rhône-Alpes
- Grenoble
- Université Joseph Fourier, Université de Grenoble
Links toward previous steps (curation, corpus...)
- to stream Hal, to step Corpus: 000239
- to stream Hal, to step Curation: 000239
- to stream Hal, to step Checkpoint: 000A07
- to stream Main, to step Merge: 002822
- to stream Main, to step Curation: 002580
Le document en format XML
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<front><div type="abstract" xml:lang="en">This work addresses the spatial correlation between the anatomical and functional human subthalamic nucleus (STN). The anatomical STN (A-STN), derived from the Schaltenbrand-Wahren brain atlas, is histology based. The functional STN (F-STN) is probabilistic, constructed from neuroelectrophysiological and neuroimaging data of 184 Parkinson's disease patients. The A-STN and F-STN are placed in the same space and compared in terms of mutual relative overlapping of anatomy with function. The F-STN and A-STN correlate well for medium and high probabilities of the F-STN. For probability p >or= 0.3, >95% of F-STN is inside the A-STN, and for p >or= 0.5, the complete F-STN is inside the A-STN for each left and right STN. Therefore, the F-STN for p = 0.5 can potentially be used for identification of the STN in neuroimages.</div>
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